2017-8-11 16:0:3Tue Dec 13 2016 11:16:36 GMT+0100 (CET)
proteinLength
292
geneLength
876
Gene
Coordinates
3,348,825 → 3,349,703
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A560 (yurN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/560 NBRP B. subtilis, Japan]
aminos
MVNQNKIIPYLFLVPALVFLLFVYIPIFENVFLSLFQWSSFSPEKTFIGLKNYVELFHDPVFYQALTNNVLYAVISIVCQVFGGLILAAVLEDKLVRKWSPFFRTVFFLPVVISMTVIALLFDFIYNPETGLLNQLLQAIGLDQLTRAWLGDDSTAMLSVIFVSQWQSVGYIAMLYIVSIQKIPDELYEAARLDGAGKIQQFFHITVPQTKEMSFVAVVMTLTGAFTVFNEPYILTGGGPGKASEVLSTFLYKSAFTKDMMGYASAIATVVLIITLALSLMQMKFFKTGKEE
[SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|utilization of specific carbon sources], [SW|utilization of nitrogen sources other than amino acids], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
3,348,825 -> 3,349,703
The protein
[SW|Interactions]
[[protein|YurJ]]-([[protein|FrlM]]-[[protein|FrlN]])-[[protein|FrlO]] [Pubmed|10092453]
Expression and Regulation
Operon
''[[protein|frlB]]-[[protein|frlO]]-[[protein|frlN]]-[[protein|frlM]]-[[protein|frlD]]'' [Pubmed|23175651,21347729]
Expression and Regulation
Regulation
'' [[protein|frlB]]'': repressed during growth in the presence of branched chain amino acids ([[protein|CodY]]) [Pubmed|12618455]
''[[protein|frlB]]'': induced in the presence of fructosamine ([[protein|FrlR]]) [Pubmed|21398478]
Expression and Regulation
Regulatory mechanism
[[protein|CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed1], [http://www.ncbi.nlm.nih.gov/sites/entrez/18083814 PubMed2]
[[protein|FrlR]]: transcription repression [Pubmed|21398478]
Expression and Regulation
Additional information
the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] [PubMed|21815947]
the ''[[protein|frlB]]-[[protein|frlO]]-[[protein|frlN]]-[[protein|frlM]]-[[protein|frlD]]'' operon is not expressed in a ''[SW|cshA]'' mutant [PubMed|23175651]
the ''[[protein|frlB]]-[[protein|frlO]]-[[protein|frlN]]-[[protein|frlM]]-[[protein|frlD]]'' operon is not expressed in the presence of [SW|NusA] [http://www.nature.com/articles/nmicrobiol20157 Reference]